Additionally, the use of conventional CV drugs to counteract ICIs detrimental effects should be investigated

Additionally, the use of conventional CV drugs to counteract ICIs detrimental effects should be investigated. that this large immune cell infiltrates predominantly consisted of cytotoxic T cells and macrophages, suggesting that both lymphoid and myeloid immune cells drive inflammation in ICI-associated myocarditis.16 Although the majority of acute IRAEs can be Continue Reading

Related relative mRNA expression was calculated by the 2 2?Cq method and normalized to -actin [18]

Related relative mRNA expression was calculated by the 2 2?Cq method and normalized to -actin [18]. was confirmed in MLE-12 cells Cell Death Detection Kit (Roche, USA) according to the manufacturers instructions. Briefly, sections (4?m) were deparaffinized in xylene, rehydrated in decreasing concentrations of ethanol, rehydrated and heated for antigen Continue Reading