The incidence of high-risk patients, defined as QTc?470?ms (Trinkley em et al /em , 2013), increased during treatment with a TKI

The incidence of high-risk patients, defined as QTc?470?ms (Trinkley em et al /em , 2013), increased during treatment with a TKI. females than in males (QTcfemales=404?ms QTcmales=399?ms, (TdP) (El-Sherif and Turitto, 2003; Moss, 2003; Trinkley studies exhibited that lapatinib and imatinib interact with the phosphorylation of the cardiac hERG channel. Continue Reading