Aside from the expected binding by E2A, this evaluation demonstrated enrichment for RUNX1, TCF7, LEF1, GATA3, and RORt motifs inside our peaks, deeming them as potential companions of E2A in L-DKO DP and iNKT cells (Shape ?(Shape2B;2B; Shape S1B in Supplementary Materials). rearrangement in Id-deficient DP cells that promotes selection Continue Reading