There was no apparent relationship between the strength of Trop-2 expression and depth of antitumor response. Pharmacokinetics Pharmacokinetic data were available for dose ranges 0.15 to 4.8 mg/kg. disease in 11 patients (37.9%). None of the patients had a partial or complete response. Systemic exposure of PF-06664178 Akt1s1 increased in Continue Reading