For instance, HMGB1 induces apoptosis of mouse macrophages in a dose- and time-dependent manner [120,121]

For instance, HMGB1 induces apoptosis of mouse macrophages in a dose- and time-dependent manner [120,121]. homology, while the rat and mouse homologues have identical amino acid sequences [40]. The DNA-binding domain name of HMGB1 comprises an A-box domain name (residues 9C79) and B-box domain name (residues 95C163), separated by a Continue Reading