Immunology 5, e117. (IgG) creation. Thus, DENV/ZIKV-cross-reactive Compact disc4+ T cells creating canonical Th1 cytokines can suppress ZIKV replication within an antibody-independent way. These outcomes may have essential implications for raising the efficiency and protection of DENV/ZIKV vaccines as well as for developing pan-flavivirus vaccines. Graphical Abstract In Short Wen Continue Reading