To determine whether PDI and ERp57 share substrate specificity, we performed kinetic trapping experiments in platelet-rich plasma with ERp57 using ERp57-CCCC, ERp57-CACC, ERp57-CCCA, ERp57-CACA, and ERp57-AAAA. vascular injury may serve as a regulatory switch that allows activation of proteins, among them vitronectin, critical for thrombus formation. Thrombus formation is usually Continue Reading