The rationale because of this study was predicated on reports that CGRP-containing trigeminal nerve fibers can be found in the synovial membrane, articular drive, periosteum, and joint capsule from the TMJ [10,11] and high concentrations of CGRP in TMJ synovial fluid are indicative of mobility impairment and pain connected with arthritis [12] and inflammation [13]

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The rationale because of this study was predicated on reports that CGRP-containing trigeminal nerve fibers can be found in the synovial membrane, articular drive, periosteum, and joint capsule from the TMJ [10,11] and high concentrations of CGRP in TMJ synovial fluid are indicative of mobility impairment and pain connected with Continue Reading