Overall, these results showed that GPIb-IX retains its normal ligand-binding function when reconstituted in Nanodiscs. == Figure 4. In conclusion, GPIb-IX in Nanodiscs adopts native-like conformation and possesses the ability to bind its natural IMR-1 ligands, thus making Nanodisc a suitablein vitroplatform Rabbit Polyclonal to SPINK6 for further investigation on Continue Reading