(C-D) Enhanced repopulating potential ofSlug/HSCs in vivo after 5-FU treatment. providing therapeutic benefits for patients after clinical myelosuppressive treatment. == Introduction == Hematopoietic stem cells (HSCs) are rare self-renewing, multipotential cells localized within the osteoblastic and vascular niches of adult bone marrow (BM).1,2In adult BM, the earliest multipotent stem cells Continue Reading