To further investigate this aspect and given that the anti-EGFR EGa1 VHH single-domain antibody was isolated from a phage-displayed llama VHH library immunized with EGFR-positive human cells (14, 15), we studied here the impact of human EGFR expression on the liver in the 1D8N/CEGa1 toxicity profile in a liver-specific huEGFR-transgenic immunocompetent mouse (16)

To further investigate this aspect and given that the anti-EGFR EGa1 VHH single-domain antibody was isolated from a phage-displayed llama VHH library immunized with EGFR-positive human cells (14, 15), we studied here the impact of human EGFR expression on the liver in the 1D8N/CEGa1 toxicity profile in a liver-specific huEGFR-transgenic Continue Reading