Thus, arousal of Daf1 via Compact disc97 reduces the known degree of appearance of cytokines that promote autoimmunity. Discussion Previous studies show the fact that lack of Daf1 exacerbates disease in a number of autoimmune choices, including experimental autoimmune uveitis,24 EAE,3 myasthenia gravis,25 and systemic autoimmune disease in the MLR-experiments. Continue Reading